HPV-associated Cancers

Lecture 5: Oropharyngeal Cancer

Kristina R. Dahlstrom, Ph.D.

Instructor, Department of Head and Neck Surgery

Erich M. Sturgis, M.D., M.P.H.

Professor, Department of Head and Neck Surgery

Summary

“To date more than 150 types of HPV have been described. About 40 of these infect the genital tract and potentially the oral cavity and the oropharynx,” says Kristina R. Dahlstrom, Ph.D., an instructor in the Department of Head and Neck Surgery at The University of Texas MD Anderson Cancer Center. In this lecture, “Oropharyngeal Cancer: Epidemiology,” Dr. Dahlstrom describes the role of HPV in oropharyngeal cancer, risk factors for the disease, why HPV-associated cancers are becoming an epidemic, and trends and incidence in survival. She also talks about methods for prevention of HPV-related oropharyngeal cancer, which includes a newly FDA approved HPV nonavalent vaccine.

When oropharyngeal cancer is HPV-related, there typically are no symptoms, but there may be a lump in the neck. In his lecture, “Oropharyngeal Cancer: Clinical Implications of the HPV Epidemic,” Erich M. Sturgis, M.D., Professor of Head and Neck Surgery and Epidemiology, describes the pathophysiology of HPV infection and malignant transformation, as well as the clinical differences between HPV-positive cancers and HPV-negative cancers. He also discusses current clinical trials.


Oropharyngeal Cancer: Epidemiology

Learning Objectives

Upon completion of this lecture, participants will be able to:
  • Describe the epidemiology of oral HPV infection
  • Understand the role of HPV in oropharyngeal cancer
  • Describe the trends in incidence and survival for HPV-related oropharyngeal cancer
  • Describe methods for prevention of HPV-related oropharyngeal cancer

Summary and Learning Objectives: Español

Estimated Time for Completion of Part 1: 25 minutes



Lecture Transcript: English  |  Español

 

 

 

Oropharyngeal Cancer: Clinical Implications of the HPV Epidemic

Learning Objectives

Upon completion of this lecture, participants will be able to:
  • Describe the pathophysiology of HPV infection and malignant transformation
  • Understand clinical differences between HPV-positive and -negative oropharyngeal cancers
  • Understand the clinical implications of HPV in oropharyngeal cancers
  • Describe current trials

Summary and Learning Objectives: Español

Estimated Time for Completion of Part 2: 40 minutes



Lecture Transcript: English  |  Español